Clinical studies on post-transfusion hepatitis particularly non-B type

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Post-transfusion hepatitis: impact of non-A, non-B hepatitis surrogate tests. Canadian Post-Transfusion Hepatitis Prevention Study Group.

Canada has not introduced the non-A, non-B (NANB) surrogate marker tests (antibodies to hepatitis B core antigen and alanine aminotransferase) to screen donated blood. We evaluated the effect of NANB surrogate markers in reducing post-transfusion hepatitis in a prospective randomised intervention study. From 1988 to 1992, 4588 subjects were enrolled into two study groups that received allogenei...

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Post-transfusion non-A, non-B hepatitis in the Netherlands.

tions and hospital admissions (r=09; p<0 01). There was a tendency throughout the period, when the figures for whooping cough increased, for the number of notifications to increase proportionately more than the number of admissions. In the peak quarters of 1974 and 1978 there were 25 and 58 admissions and 159 and 666 notifications respectively. We studied Hospital Activity Analysis statistics f...

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STUDIES ON HEPATITIS B VACCINES

HBs vaccines were prepared by three different methods: 1) Heat inactivation (Krugman, et.al 1971)2) Ammonium sulphate precipitation followed by column chromatography (Sephadex G-200) 3) PEG-6000 (polyethylene glycol) precipitation followed by column chromatography using Sephadex G-200. Their efficacy was studied in guinea pigs, and the results compared with commercial Japanese vaccine (Gr...

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The dominant role of non-A, non-B in the pathogenesis of post-transfusion hepatitis: a clinical assessment.

Although clinically recognized since the time of Hippocrates, viral hepatitis has been a continually enigmatic disease with each new insight raising the spectre of a new complexity. Despite remarkable advances in the past decade emanating from the discovery of the Australia antigen (Blumberg, Alter and Visnich, 1965) and its eventual linkage to viral hepatitis type B (Prince, 1968), there remai...

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Post-transfusion non-A, non-B hepatitis in Finland: a prospective study.

To study the frequency of post-transfusion non-A, non-B (NANB) hepatitis in Finland, we have followed prospectively 65 patients after open-heart surgery. The total number of transfused blood units was 652. Blood samples were obtained from the patients during the first 6 months after the operation and were studied for transaminase levels. The NANB diagnosis was based on exclusion of viral hepati...

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ژورنال

عنوان ژورنال: Kanzo

سال: 1980

ISSN: 0451-4203,1881-3593

DOI: 10.2957/kanzo.21.713